作者
Ahmed N Mahmoud, Amgad Mentias, Akram Y Elgendy, Abdul Qazi, Amr F Barakat, Marwan Saad, Ala Mohsen, Ahmed Abuzaid, Hend Mansoor, Mohammad K Mojadidi, Islam Y Elgendy
发表日期
2018/3/1
期刊
BMJ open
卷号
8
期号
3
页码范围
e020498
出版商
British Medical Journal Publishing Group
简介
Objectives
To perform an updated meta-analysis to evaluate the long-term cardiovascular and cerebrovascular outcomes among migraineurs.
Setting
A meta-analysis of cohort studies performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.
Data sources
The MEDLINE, Web of Science and Cochrane Central Register of Controlled Trials databases were searched for relevant articles.
Participants
A total of 16 cohort studies (18 study records) with 394 942 migraineurs and 757 465 non-migraineurs were analysed.
Primary and secondary outcome measures
Major adverse cardiovascular and cerebrovascular events (MACCE), stroke (ie, ischaemic, haemorrhagic or non-specified), myocardial infarction (MI) and all-cause mortality. The outcomes were reported at the longest available follow-up.
Data analysis
Summary-adjusted hazard ratios (HR) were calculated by …
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AN Mahmoud, A Mentias, AY Elgendy, A Qazi… - BMJ open, 2018