作者
Christoph Würnschimmel, Mike Wenzel, Nuowei Wang, Zhe Tian, Pierre I Karakiewicz, Markus Graefen, Hartwig Huland, Derya Tilki
发表日期
2021/12/1
期刊
Urologic Oncology: Seminars and Original Investigations
卷号
39
期号
12
页码范围
830. e17-830. e26
出版商
Elsevier
简介
Introduction
Long-term outcomes of prostate cancer (CaP) patients treated with radical prostatectomy (RP) from European cohorts are under-reported. We report on 22,843 RP patients from the Martini-Klinik Prostate Cancer Centre treated between 1992 and 2017.
Patients and Methods
Biochemical recurrence (BCR) free survival, metastasis free survival (MFS), and cancer specific survival (CSS) were stratified according to National Comprehensive Cancer Network (NCCN) risk categories, pT, and pN stages, RP Gleason Grade Groups (GGG), and surgical margin status (R0/R1). For time to event analyses, uni- and multivariable Cox's proportional hazards models and univariable Kaplan-Meier analyses were applied.
Results
Median follow up was 68 months. Most favourable 20-year survival rates were exhibited in NCCN low risk (78.7% BCR-free, 96.8% MFS, 90.1% CSS) and pT2, GGG 1 to 2, R0 patients (83.1 …
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C Würnschimmel, M Wenzel, N Wang, Z Tian… - Urologic Oncology: Seminars and Original …, 2021