作者
Jennifer Wang
发表日期
2010
期刊
NNIN REU Research Accomplishments
页码范围
32-33
简介
The goal of this project included fabricating uniform porous poly (lactic-co-glycolic) acid (PLGA) microbeads using a fluidic device, seeding fibroblasts into these beads, and culturing these cell-loaded beads in a mold of a desired shape. The fibroblasts attached and proliferated in porous beads with average pore diameters of 30 µm. These fibroblast-loaded beads connected to neighboring beads by a network of cells and extracellular matrices (ECM) to form the beginnings of a tissue construct inside the mold. These preliminary results have promising implications, such as the possibility of creating shape-specific tissues to better fit injury sites.
引用总数