作者
Yi-Ting Hsieh, Minhaj Nur Alam, David Le, Chia-Chieh Hsiao, Chang-Hao Yang, Daniel L Chao, Xincheng Yao
发表日期
2019/10/1
期刊
Ophthalmology Retina
卷号
3
期号
10
页码范围
826-834
出版商
Elsevier
简介
Purpose
To correlate quantitative OCT angiography (OCTA) biomarkers with clinical features and to predict the extent of visual improvement after ranibizumab treatment for diabetic macular edema (DME) with OCTA biomarkers.
Design
Retrospective, longitudinal study in Taiwan.
Participants
Fifty eyes of 50 patients with DME and 22 eyes of 22 healthy persons, with the exception of cataract and refractive error, from 1 hospital.
Methods
Each eye underwent OCT angiography (RTVue XR Avanti System with AngioVue software version 2017.1; Optovue, Fremont, CA), and 3×3-mm2 en face OCTA images of the superficial layer and the deep layer were obtained at baseline and after 3 monthly injections of ranibizumab in the study group. OCT angiography images also were acquired from the control group.
Main Outcome Measures
Five OCTA biomarkers, including foveal avascular zone (FAZ) area (FAZ-A), FAZ contour …
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YT Hsieh, MN Alam, D Le, CC Hsiao, CH Yang… - Ophthalmology Retina, 2019