作者
David A Fitzmaurice, Gabriele Accetta, Sylvia Haas, Gloria Kayani, Hector Lucas Luciardi, Frank Misselwitz, Karen Pieper, Hugo Ten Cate, Alexander GG Turpie, Ajay K Kakkar, GARFIELD‐AF Investigators, Jean‐Pierre Bassand, A John Camm, Samuel Z Goldhaber, Shinya Goto, Werner Hacke, Lorenzo G Mantovani, Martin van Eickels, Freek WA Verheugt, Keith AA Fox, Bernard J Gersh, Harry Gibbs, Marianne Brodmann, Frank Cools, Antonio Carlos Pereira Barretto, Stuart J Connolly, Alex Spyropoulos, John Eikelboom, Ramon Corbalan, Dayi Hu, Petr Jansky, Jørn Dalsgaard Nielsen, Hany Ragy, Pekka Raatikainen, Jean‐Yves Le Heuzey, Harald Darius, Matyas Keltai, Sanjay Kakkar, Jitendra Pal Singh Sawhney, Giancarlo Agnelli and Giuseppe Ambrosio, Yukihiro Koretsune, Carlos Jerjes Sánchez Díaz, Dan Atar, Janina Stepinska, Elizaveta Panchenko, Toon Wei Lim, Barry Jacobson, Seil Oh, Xavier Viñolas, Marten Rosenqvist, Jan Steffel, Pantep Angchaisuksiri, Ali Oto, Alex Parkhomenko, Wael Al Mahmeed, DY Hu, KN Chen, YS Zhao, HQ Zhang, JZ Chen, SP Cao, DW Wang, YJ Yang, WH Li, YH Yin, GZ Tao, P Yang, YM Chen, SH He, Y Wang, Y Wang, GS Fu, X Li, TG Wu, XS Cheng, XW Yan, RP Zhao, MS Chen, LG Xiong, P Chen, Y Jiao, Y Guo, L Xue, FZ Wang, H Li, ZM Yang, CL Bai, J Chen, JY Chen, X Chen, S Feng, QH Fu, XJ Gao, WN Guo, RH He, XA He, XS Hu, XF Huang, B Li, J Li, L Li, YH Li, TT Liu, WL Liu, YY Liu, ZC Lu, XL Luo, TY Ma, JQ Peng, X Sheng, XJ Shi, YH Sun, G Tian, K Wang, L Wang, RN Wu, Q Xie, RY Xu, JS Yang, LL Yang, Q Yang, YJ Yang, Y Ye, HY Yu, JH Yu, T Yu, H Zhai, Q Zhan, GS Zhang, Q Zhang, R Zhang, Y Zhang, WY Zheng, B Zhou, ZH Zhou, XY Zhu, S Kakkar, JPS Sawhney, P Jadhav, R Durgaprasad, AG Ravi Shankar, RK Rajput, K Bhargava, R Sarma, A Srinivas, D Roy, UM Nagamalesh, M Chopda, R Kishore, G Kulkarni
发表日期
2016/8
期刊
British journal of haematology
卷号
174
期号
4
页码范围
610-623
简介
Vitamin K antagonist (VKA) therapy for stroke prevention in atrial fibrillation (AF) requires monitoring of the international normalized ratio (INR). We evaluated the agreement between two INR audit parameters, frequency in range (FIR) and proportion of time in the therapeutic range (TTR), using data from a global population of patients with newly diagnosed non‐valvular AF, the Global Anticoagulant Registry in the FIELD–Atrial Fibrillation (GARFIELD‐AF). Among 17 168 patients with 1‐year follow‐up data available at the time of the analysis, 8445 received VKA therapy (±antiplatelet therapy) at enrolment, and of these patients, 5066 with ≥3 INR readings and for whom both FIR and TTR could be calculated were included in the analysis. In total, 70 905 INRs were analysed. At the patient level, TTR showed higher values than FIR (mean, 56·0% vs 49·8%; median, 59·7% vs 50·0%). Although patient‐level FIR and …
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DA Fitzmaurice, G Accetta, S Haas, G Kayani… - British journal of haematology, 2016