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Combat injuries can result in severe acute pain, and options for pain control on the battlefield are currently limited. There is a need for improved pain control on the battlefield, as well as in higher echelons of casualty care. Initial pain control can increase patient comfort and aid in evacuation from the point of injury [1-3]. The development of novel analgesic agents may identify medications that produce decreased side effects as compared to morphine, which can result in respiratory depression, immunosuppression, hemodynamic effects, and cognitive deficits [4, 5]. The ultimate goal of Force Health Protection (FHP) is to preserve the fighting force [6-8], and pain is the ultimate performance degrader for Service Members. The implementation of more effective pain control on the battlefield will affect not only individual Service Members but also overall mission accomplishment. Additionally, effective initial pain control can decrease the incidence of chronic pain development, which could affect return to duty rates, and can also reduce patient care and rehabilitation expenses.