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Roles of selected factors on sex reversal of fry of Mozambique tilapia (Tilapia mossambica) administered 17∝‐methyltestosterone (MT) through the diet were investigated. The tested factors were temperature (22–38°C), photoperiod (darkness: light, 0 h:24 h to 24 h:0 h), stocking density (100–2,000 fry/m²), feeding rate (10 or 25% body weight!d), supplementation of the medium with a growth promotor (thyroxine), and storage conditions of MT and MT‐treated feed. Survival, growth, and sex‐reversing potency of MT were significantly influenced directly or indirectly by temperature, feeding rate, photoperiod, and storage conditions of both MT and MT‐treated feed. Stocking density and supplementation of thyroxine in the rearing medium influenced survival and growth. without modifying the sex‐reversing potency of MT, when the treated fry were fed ad libitum. Photoperiod and low rearing temperature did not directly …