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Fatigue is a well‐established symptom in systemic lupus erythematosus (SLE), but has not been well characterized in other skin‐limited autoimmune diseases such as cutaneous lupus erythematosus (CLE), amyopathic dermatomyositis (ADM) or autoimmune blistering diseases (AIBD).

In this retrospective study, we compared fatigue in controls (n = 84) with that in patients enrolled in prospective longitudinal databases with SLE (n = 165), CLE (n = 226), ADM (n = 136) and AIBD (n = 79).

We used the 36‐Item Short Form Survey (SF‐36) vitality scale to analyse median scores and the percentages of patients with clinically significant fatigue (defined as a score ≤ 35) between experimental groups and controls.

Median and interquartile range (IQR) vitality scores demonstrated greater fatigue in the …