作者
Hyung Jun Im, Tae Sung Kim, Seog-Yun Park, Hye Sook Min, June Hyuk Kim, Hyun Guy Kang, Seung Eun Park, Mi Mi Kwon, Jong Hyung Yoon, Hyeon Jin Park, Seok-ki Kim, Byung-Kiu Park
发表日期
2012/1
期刊
European journal of nuclear medicine and molecular imaging
卷号
39
页码范围
39-49
出版商
Springer-Verlag
简介
Purpose
The utility of combined metabolic and volumetric 18F-FDG PET/CT indices for predicting tumour necrosis fractions following neoadjuvant chemotherapy has not been extensively studied in osteosarcoma. Furthermore, little is known of the early PET/CT responses after only one chemotherapy course.
Methods
Enrolled in the study were 20 children and young adults with resectable osteosarcoma who had undergone 18F-FDG PET/CT scans before and after neoadjuvant chemotherapy. Maximum standardized uptake value (mSUV), metabolic tumour volume (MTV), and total lesion glycolysis (TLG) were measured. From among the 20 patients, 14 were prospectively recruited and underwent an additional PET/CT scan after one chemotherapy course. Histopathological necrosis fractions were compared with the above-mentioned PET/CT indices and …
学术搜索中的文章
HJ Im, TS Kim, SY Park, HS Min, JH Kim, HG Kang… - European journal of nuclear medicine and molecular …, 2012