作者
Jan Scott, Greg Murray, Chantal Henry, Gunnar Morken, Elizabeth Scott, Jules Angst, Kathleen R Merikangas, Ian B Hickie
发表日期
2017/2/1
来源
JAMA psychiatry
卷号
74
期号
2
页码范围
189-196
出版商
American Medical Association
简介
Importance
Increased activity and energy alongside mood change are identified in theDSM-5as cardinal symptoms of mania and hypomania. A wide range of existing research suggests that this revision may be valid, but systematic integration of the evidence has not been reported. The termactivationis understood as emerging from underlying physiological change and having objective (observable motor activity) and related subjective (energy) levels.
Objectives
To systematically review studies of the clinical phenomenon of activation in bipolar disorder, to determine whether activation is statistically abnormal in bipolar disorder and demonstrably distinct from mood, and to identify any significant between- and within-individual differences in the dynamics of activation.
Evidence Review
This systematic review of MEDLINE, PsycINFO, EMBASE, CINAHL, and PubMed databases from January 1, 1970, until September 30 …
学术搜索中的文章
J Scott, G Murray, C Henry, G Morken, E Scott, J Angst… - JAMA psychiatry, 2017