作者
Ching-Jen Chen, Dale Ding, Robert M Starke, Prachi Mehndiratta, R Webster Crowley, Kenneth C Liu, Andrew M Southerland, Bradford B Worrall
发表日期
2015/12/1
来源
Neurology
卷号
85
期号
22
页码范围
1980-1990
出版商
Lippincott Williams & Wilkins
简介
Objective
To compare the outcomes between endovascular and medical management of acute ischemic stroke in recent randomized controlled trials (RCT).
Methods
A systematic literature review was performed, and multicenter, prospective RCTs published from January 1, 2013, to May 1, 2015, directly comparing endovascular therapy to medical management for patients with acute ischemic stroke were included. Meta-analyses of modified Rankin Scale (mRS) and mortality at 90 days and symptomatic intracranial hemorrhage (sICH) for endovascular therapy and medical management were performed.
Results
Eight multicenter, prospective RCTs (Interventional Management of Stroke [IMS] III, Local Versus Systemic Thrombolysis for Acute Ischemic Stroke [SYNTHESIS] Expansion, Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy [MR RESCUE], Multicenter Randomized Clinical Trial of …
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CJ Chen, D Ding, RM Starke, P Mehndiratta… - Neurology, 2015