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Sargassum polycystum, a brown seaweed, contains various nutrients and bioactive compounds that have antioxidant and healing properties. The research hypothesises that antioxidants and pigments in dietary S. polycystum extracts can improve insulin sensitivity, blood sugar levels and blood lipid levels in a rat model of type 2 diabetes. The diabetes was induced by a high‐sugar, high‐fat diet for 16 weeks to enhance insulin resistance, followed by a low‐dose intraperitoneal injection of streptozotocin (35 mg kg⁻¹ body weight). The doses of S. polycystum tested on diabetic rats were 150 and 300 mg kg⁻¹ body weight for the ethanolic extract or 150 and 300 mg kg⁻¹ for the water extract. Normal rats, untreated diabetic and metformin‐treated diabetic rats (n = 6) were used as control.

Both doses of the alcohol extract of S. polycystum and the 300 mg kg⁻¹ water extract, significantly …