作者
MH Pourgholami, S Majzoob, M Javadi, M Kamalinejad, GHR Fanaee, M Sayyah
发表日期
1999/8/1
期刊
Journal of ethnopharmacology
卷号
66
期号
2
页码范围
211-215
出版商
Elsevier
简介
This study investigates anticonvulsant effects of an essential oil of the fruits of Pimpinella anisum (Umbelliferae), a folkloric remedy in the Iranian traditional medicine, against seizures induced by pentylenetetrazole (PTZ) or maximal electroshock (MES) in male mice. The essential oil suppressed tonic convulsions induced by PTZ or MES. It also elevated the threshold of PTZ-induced clonic convulsions in mice. The essential oil produced motor impairment. However, this effect was not observed at the doses and time courses needed for anticonvulsant activity.
引用总数
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MH Pourgholami, S Majzoob, M Javadi, M Kamalinejad… - Journal of ethnopharmacology, 1999