作者
Katharina Gapp, Ali Jawaid, Peter Sarkies, Johannes Bohacek, Pawel Pelczar, Julien Prados, Laurent Farinelli, Eric Miska, Isabelle M Mansuy
发表日期
2014/5
期刊
Nature neuroscience
卷号
17
期号
5
页码范围
667-669
出版商
Nature Publishing Group US
简介
Small non-coding RNAs (sncRNAs) are potential vectors at the interface between genes and environment. We found that traumatic stress in early life altered mouse microRNA (miRNA) expression, and behavioral and metabolic responses in the progeny. Injection of sperm RNAs from traumatized males into fertilized wild-type oocytes reproduced the behavioral and metabolic alterations in the resulting offspring.
学术搜索中的文章
K Gapp, A Jawaid, P Sarkies, J Bohacek, P Pelczar… - Nature neuroscience, 2014