作者
Daniel T Myran, Lyndsay D Harrison, Michael Pugliese, Marco Solmi, Kelly K Anderson, Jess G Fiedorowicz, Christopher M Perlman, Colleen Webber, Yaron Finkelstein, Peter Tanuseputro
发表日期
2023/11/1
期刊
JAMA psychiatry
卷号
80
期号
11
页码范围
1169-1174
出版商
American Medical Association
简介
Importance
Episodes of substance-induced psychosis are associated with increased risk of developing a schizophrenia spectrum disorder. However, there are limited data on the transition risk for substance use without psychosis.
Objectives
To quantify the risk of transition to schizophrenia spectrum disorder following an incident emergency department (ED) visit for (1) substance-induced psychosis and (2) substance use without psychosis and to explore factors associated with transition.
Design, Settings, and Participants
A population-based retrospective cohort study (January 2008 to March 2022) of all individuals, aged 14 to 65 years, in Ontario, Canada, with no history of a psychotic disorder. Individuals with incident ED visits for substance use with and without psychosis were compared with members of the general population.
Main Outcomes and Measures
Transition to schizophrenia spectrum disorder using a chart …
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DT Myran, LD Harrison, M Pugliese, M Solmi… - JAMA psychiatry, 2023