作者
Susan J Skledar, Brian A Williams, Manuel C Vallejo, Patricia L Dalby, Jonathan H Waters, Ronald Glick, Michael L Kentor
发表日期
2007
来源
The Scientific World Journal
卷号
7
期号
1
页码范围
959-977
出版商
TheScientificWorldJOURNAL
简介
For ondansetron, dexamethasone, and droperidol (when used for prophylaxis), each is estimated to reduce risk of postoperative nausea and/or vomiting (PONV) by approximately 25%. Current consensus guidelines denote that patients with 0–1 risk factors still have a 10–20% risk of encountering PONV, but do not yet advocate routine prophylaxis for all patients with 10–20% risk. In ambulatory surgery, however, multimodal prophylaxis has gained favor, and our previously published experience with routine prophylaxis has yielded PONV rates below 10%. We now propose a “zero‐tolerance” antiemetic algorithm for outpatients that involves routine prophylaxis by first avoiding volatile agents and opioids to the extent possible, using locoregional anesthesia, multimodal analgesia, and low doses of three nonsedating off‐patent antiemetics. Routine oral administration (immediately on arrival to the ambulatory surgery …
学术搜索中的文章
SJ Skledar, BA Williams, MC Vallejo, PL Dalby… - The Scientific World Journal, 2007