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The application of a currently proposed differential privacy algorithm to the 2020 United States Census data and additional data products may affect the usefulness of these data, the accuracy of estimates and rates derived from them, and critical knowledge about social phenomena such as health disparities. We test the ramifications of applying differential privacy to released data by studying estimates of US mortality rates for the overall population and three major racial/ethnic groups. We ask how changes in the denominators of these vital rates due to the implementation of differential privacy can lead to biased estimates. We situate where these changes are most likely to matter by disaggregating biases by population size, degree of urbanization, and adjacency to a metropolitan area. Our results suggest that differential privacy will more strongly affect mortality rate estimates for non-Hispanic blacks and Hispanics …