作者
Shuzhong He, Wei Yang, Lizhi Zhu, Guangyan Du, Chi-Sing Lee
发表日期
2014/1/17
期刊
Organic letters
卷号
16
期号
2
页码范围
496-499
出版商
American Chemical Society
简介
The first and protective group-free total synthesis of (±)-yezo’otogirin C has been achieved from 3-methyl-4-prenylcyclohex-2-enone in eight steps with 23% overall yield. The tricyclic core of (±)-yezo’otogirin C was established via a bioinspired oxidative cascade cyclization strategy using Mn(II)/Mn(III) and O2, followed by reduction of the peroxy-bridged intermediate using thiourea in refluxing methanol.
学术搜索中的文章
S He, W Yang, L Zhu, G Du, CS Lee - Organic letters, 2014