作者
Yu Hohri, Satoshi Numata, Keiichi Itatani, Keiichi Kanda, Sachiko Yamazaki, Tomoya Inoue, Hitoshi Yaku
发表日期
2021/8/1
期刊
European Journal of Cardio-Thoracic Surgery
卷号
60
期号
2
页码范围
384-391
出版商
Oxford University Press
简介
OBJECTIVES
The actual underlying mechanisms of acute type A aortic dissection (AAAD) are not well understood. The present study aimed to elucidate the mechanism of AAAD using computational fluid dynamics (CFD) analysis.
METHODS
We performed CFD analysis using patient-specific computed tomography imaging in 3 healthy control cases and 3 patients with AAAD. From computed tomography images, we made a healthy control model or pre-dissection model for CFD analysis. Pulsatile cardiac flow during one cardiac cycle was simulated, and a three-dimensional flow streamline was visualized to evaluate flow velocity, wall shear stress and oscillatory shear index (OSI).
RESULTS
In healthy controls, the transvalvular aortic flow was parallel to the ascending aorta. There was no spotty high OSI area at the …
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Y Hohri, S Numata, K Itatani, K Kanda, S Yamazaki… - European Journal of Cardio-Thoracic Surgery, 2021