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The antibacterial effect of citric acid for antibiotic resistant Pseudomonas aeruginosa was studied. Twenty-five clinical isolates were tested and all were inhibited by 2% citric acid in a broth dilution assay. Topical application of 2–3% citric acid to wounds, for three to seven times, successfully eliminated P. aeruginosa from the site. The use of this agent is therefore recommended as an effective and economical approach to the control of multiple antibiotic resistant strains of P. aeruginosa causing superficial infections.