作者
Siri Beier Jensen, Anne Marie Lynge Pedersen, Arjan Vissink, Elo Andersen, CG Brown, AN Davies, J Dutilh, JS Fulton, L Jankovic, NNF Lopes, ALS Mello, LV Muniz, CA Murdoch-Kinch, RG Nair, JJ Napeñas, A Nogueira-Rodrigues, D Saunders, B Stirling, I Von Bültzingslöwen, DS Weikel, LS Elting, FKL Spijkervet, MT Brennan, Salivary Gland Hypofunction/Xerostomia Section, Oral Care Study Group, Multinational Association of Supportive Care in Cancer (MASCC)/International Society of Oral Oncology (ISOO)
发表日期
2010/8
来源
Supportive care in cancer
卷号
18
页码范围
1061-1079
出版商
Springer-Verlag
简介
Purpose
This systematic review aimed to assess the literature for management strategies and economic impact of salivary gland hypofunction and xerostomia induced by cancer therapies and to determine the quality of evidence-based management recommendations.
Methods
The electronic databases of MEDLINE/PubMed and EMBASE were searched for articles published in English since the 1989 NIH Development Consensus Conference on the Oral Complications of Cancer Therapies until 2008 inclusive. For each article, two independent reviewers extracted information regarding study design, study population, interventions, outcome measures, results, and conclusions.
Results
Seventy-two interventional studies met the inclusion criteria. In addition, 49 intensity-modulated radiation therapy (IMRT) studies were …
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