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Objective:

The last multicentered analysis of extracorporeal membrane oxygenation in pediatric acute respiratory failure was completed in 1993. We reviewed recent international data to evaluate survival and predictors of mortality.

Design:

Retrospective case series review.

Setting:

The Extracorporeal Life Support Organization Registry, which includes data voluntarily submitted from over 115 centers worldwide, was queried. The work was completed at the Division of Pediatric Critical Care, Department of Pediatrics, Primary Children's Medical Center, University of Utah, Salt Lake City, UT.

Subjects:

Patients aged 1 month to 18 yrs supported with extracorporeal membrane oxygenation for acute respiratory failure from 1993 to 2007.

Interventions:

None.

Measurements and Main Results:

There were 3,213 children studied. Overall survival remained relatively unchanged over time at 57%. Considerable variability in survival …