作者
Vincenzo Nuzzi, Marco Merlo, Claudia Specchia, Carlo Mario Lombardi, Valentina Carubelli, Annamaria Iorio, Riccardo Maria Inciardi, Antonio Bellasi, Claudia Canale, Rita Camporotondo, Francesco Catagnano, Laura Adelaide Dalla Vecchia, Stefano Giovinazzo, Gloria Maccagni, Massimo Mapelli, Davide Margonato, Luca Monzo, Chiara Oriecuia, Giulia Peveri, Andrea Pozzi, Giovanni Provenzale, Filippo Sarullo, Daniela Tomasoni, Pietro Ameri, Massimiliano Gnecchi, Sergio Leonardi, Piergiuseppe Agostoni, Stefano Carugo, Gian Battista Danzi, Marco Guazzi, Maria Teresa La Rovere, Andrea Mortara, Massimo Piepoli, Italo Porto, Maurizio Volterrani, Michele Senni, Marco Metra, Gianfranco Sinagra
发表日期
2021/10
期刊
ESC Heart Failure
卷号
8
期号
5
页码范围
3504-3511
简介
Aims
Myocardial injury (MI) in coronavirus disease‐19 (COVID‐19) is quite prevalent at admission and affects prognosis. Little is known about troponin trajectories and their prognostic role. We aimed to describe the early in‐hospital evolution of MI and its prognostic impact.
Methods and results
We performed an analysis from an Italian multicentre study enrolling COVID‐19 patients, hospitalized from 1 March to 9 April 2020. MI was defined as increased troponin level. The first troponin was tested within 24 h from admission, the second one between 24 and 48 h. Elevated troponin was defined as values above the 99th percentile of normal values. Patients were divided in four groups: normal, normal then elevated, elevated then normal, and elevated. The outcome was in‐hospital death. The study population included 197 patients; 41% had normal troponin at both evaluations, 44% had elevated troponin at both …
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