作者
Charley Christian Staats, Angela Junges, Rafael Lucas Muniz Guedes, Claudia Elizabeth Thompson, Guilherme Loss de Morais, Juliano Tomazzoni Boldo, Luiz Gonzaga Paula de Almeida, Fabio Carrer Andreis, Alexandra Lehmkuhl Gerber, Nicolau Sbaraini, Rana Louise de Andrade da Paixao, Leonardo Broetto, Melissa Landell, Lucélia Santi, Walter Orlando Beys-da-Silva, Carolina Pereira Silveira, Thaiane Rispoli Serrano, Eder Silva de Oliveira, Livia Kmetzsch, Marilene Henning Vainstein, Ana Tereza Ribeiro de Vasconcelos, Augusto Schrank
发表日期
2014/12
期刊
BMC genomics
卷号
15
页码范围
1-18
出版商
BioMed Central
简介
Background
Metarhizium anisopliae is an entomopathogenic fungus used in the biological control of some agricultural insect pests, and efforts are underway to use this fungus in the control of insect-borne human diseases. A large repertoire of proteins must be secreted by M. anisopliae to cope with the various available nutrients as this fungus switches through different lifestyles, i.e., from a saprophytic, to an infectious, to a plant endophytic stage. To further evaluate the predicted secretome of M. anisopliae, we employed genomic and transcriptomic analyses, coupled with phylogenomic analysis, focusing on the identification and characterization of secreted proteins.
Results
We determined the M. anisopliae E6 genome sequence and compared this sequence to other entomopathogenic fungi genomes. A robust pipeline was generated to evaluate the …
学术搜索中的文章
CC Staats, A Junges, RLM Guedes, CE Thompson… - BMC genomics, 2014