作者
Florence TH Wu, Marianne O Stefanini, Feilim Mac Gabhann, Christopher D Kontos, Brian H Annex, Aleksander S Popel
发表日期
2010/3
来源
Journal of cellular and molecular medicine
卷号
14
期号
3
页码范围
528-552
出版商
Blackwell Publishing Ltd
简介
  • • 
    Introduction
    • ‐ 
      Angiogenesis in physiology and pathology
    • ‐ 
      Angiogenesis in current medicine
    • ‐ 
      VEGF ligand and receptor system: where does sVEGFR1 fit?
      • ‐ 
        Ligands: the human VEGF family
      • ‐ 
        Membrane‐bound signalling receptors: VEGFRs
      • ‐ 
        Non‐signalling co‐receptors and matrix proteins: HSPGs and NRPs
      • ‐ 
        Soluble receptors: sVEGFR1, sVEGFR2, sNRP1
  • • 
    Molecular biology of sVEGFR1
  • • 
    Physiological and pathophysiological roles of sVEGFR1
  • • 
    Molecular mechanism of sVEGFR1’s anti‐angiogenic potential
  • • 
    sVEGFR1 as a clinical marker for disease
  • • 
    Plasma VEGF and sVEGFR1: non‐uniform predictors of angiogenic status across all diseases
  • • 
    Systems biology perspective: unifying interpretation of plasma angiogenic markers
    • ‐ 
      Baseline heterogeneity in clinical measurements of healthy VEGF and sVEGFR1 levels in plasma
    • ‐ 
      Effect of sVEGFR1 on VEGF …
引用总数
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