作者
Chun-Ta Liao, Joseph Tung-Chieh Chang, Hung-Ming Wang, Shu-Hang Ng, Chuen Hsueh, Li-Yu Lee, Chih-Hung Lin, I-How Chen, Shiang-Fu Huang, Ann-Joy Cheng, Tzu-Chen Yen
发表日期
2008/3
期刊
Annals of surgical oncology
卷号
15
页码范围
915-922
出版商
Springer-Verlag
简介
Background
Survival in oral cavity squamous cell carcinoma (OSCC) depends heavily on locoregional control. In this study, we sought to determine the independent prognosticators for local tumor control, disease-specific survival (DSS), and overall survival (OS) rates in a series of OSCC patients undergoing radical surgery.
Methods
We retrospectively reviewed 827 consecutive OSCC patients undergoing radical surgery from January 1998 to March 2005. Postoperative radiotherapy was performed in patients with pT4 tumors, positive lymph node(s), or close margins (≤4 mm). Local control rates and survivals were plotted using the Kaplan–Meier method.
Results
On multivariate analysis (MVA), unfavorable prognostic factors for local control were pathological margins ≤7 mm (P < 0.001), pathological tumor depth ≥10 …
引用总数
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CT Liao, JTC Chang, HM Wang, SH Ng, C Hsueh… - Annals of surgical oncology, 2008