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Aim  The concurrent, construct and discriminative validity of the World Health Organization's Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) were examined in a multi‐site international study.

Participants  One thousand and 47 participants, recruited from drug treatment (n = 350) and primary health care (PHC) settings (n = 697), were administered a battery of instruments.

Measurements  Measures included the ASSIST; the Addiction Severity Index‐Lite (ASI‐Lite); the Severity of Dependence Scale (SDS); the MINI International Neuropsychiatric Interview (MINI‐Plus); the Rating of Injection Site Condition (RISC); the Drug Abuse Screening Test (DAST); the Alcohol Use Disorders Identification Test (AUDIT); the Revised Fagerstrom Tolerance Questionnaire (RTQ); and the Maudsley Addiction Profile (MAP).

Findings  Concurrent validity was demonstrated by significant correlations …