作者
Guopei Luo, Ammar Javed, Jonathan R Strosberg, Kaizhou Jin, Yu Zhang, Chen Liu, Jin Xu, Kevin Soares, Matthew J Weiss, Lei Zheng, Christopher L Wolfgang, Mauro Cives, Joyce Wong, Wei Wang, Jian Sun, Chenghao Shao, Wei Wang, Huangying Tan, Jie Li, Quanxing Ni, Lin Shen, Minhu Chen, Jin He, Jie Chen, Xianjun Yu
发表日期
2017/1/20
期刊
Journal of Clinical Oncology
卷号
35
期号
3
页码范围
274-280
出版商
American Society of Clinical Oncology
简介
Purpose
The European Neuroendocrine Tumor Society (ENETS) and the American Joint Committee on Cancer (AJCC) staging classifications are two widely used systems in managing pancreatic neuroendocrine tumors. However, there is no universally accepted system.
Methods
An analysis was performed to evaluate the application of the ENETS and AJCC staging classifications using the SEER registry (N = 2,529 patients) and a multicentric series (N = 1,143 patients). A modified system was proposed based on analysis of the two existing classifications. The modified system was then validated.
Results
The proportion of patients with AJCC stage III disease was extremely low for both the SEER series (2.2%) and the multicentric series (2.1%). For the ENETS staging system, patients with stage I disease had a similar prognosis to patients with stage IIA disease, and patients with stage IIIB disease had a lower hazard …
学术搜索中的文章
G Luo, A Javed, JR Strosberg, K Jin, Y Zhang, C Liu… - Journal of Clinical Oncology, 2017