作者
Peter J Allen, Deborah Kuk, Carlos Fernandez-del Castillo, Olca Basturk, Christopher L Wolfgang, John L Cameron, Keith D Lillemoe, Cristina R Ferrone, Vicente Morales-Oyarvide, Jin He, Matthew J Weiss, Ralph H Hruban, Mithat Gönen, David S Klimstra, Mari Mino-Kenudson
发表日期
2017/1/1
期刊
Annals of surgery
卷号
265
期号
1
页码范围
185-191
出版商
LWW
简介
Objective:
The aim of this study was to evaluate and validate the proposed 8th edition American Joint Committee on Cancer (AJCC) system for T and N staging of pancreatic adenocarcinoma.
Summary of Background Data:
Investigators have questioned the clinical relevance and reproducibility of previous AJCC staging for pancreatic adenocarcinoma.
Methods:
Prospective databases at Memorial Sloan Kettering (MSK), Massachusetts General Hospital (MGH), and Johns Hopkins Hospital (JHH) were queried for patients who had undergone resection for pancreatic adenocarcinoma. Patients who underwent a margin-negative (R0) resection, and who had previously undergone pathologic review, were included. Patients were staged according to 7th edition AJCC criteria, as well as the proposed 8th edition system that includes different definitions of tumor size (T) and nodal status (N). The dataset was randomly split …
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PJ Allen, D Kuk, C Fernandez-del Castillo, O Basturk… - Annals of surgery, 2017