作者
Jin He, John L Cameron, Nita Ahuja, Martin A Makary, Kenzo Hirose, Michael A Choti, Richard D Schulick, Ralph H Hruban, Timothy M Pawlik, Christopher L Wolfgang
发表日期
2013/4/1
期刊
Journal of the American College of Surgeons
卷号
216
期号
4
页码范围
657-665
出版商
Elsevier
简介
BACKGROUND
Little is known about the risk of subsequently developing a new or progressive intraductal papillary mucinous neoplasm (IPMN) after partial pancreatic resection of a noninvasive IPMN.
STUDY DESIGN
One hundred thirty patients with more than 1 year of follow-up after resection were included in this analysis.
RESULTS
At a median follow-up of 38 months, 22 (17%) developed imaging evidence of a new or progressive IPMN. Eleven (8%) underwent completion resection. Three of the 11 patients had invasive adenocarcinoma. Two other patients developed metastatic pancreatic adenocarcinoma and did not undergo resection. All 5 patients (4%) with cancer had negative margins at initial operation. Sixteen of 100 patients (16%) with negative margins for IPMN at the initial operation developed a new IPMN vs 6 of 30 patients (20%) with margins positive for IPMN (p = ns). Five of 22 patients (23%) with …
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J He, JL Cameron, N Ahuja, MA Makary, K Hirose… - Journal of the American College of Surgeons, 2013