作者
LC Martins, VN Figueiredo, T Quinaglia, L Boer-Martins, JC Yugar-Toledo, JFV Martin, C Demacq, E Pimenta, DA Calhoun, H Moreno Jr
发表日期
2011/9
期刊
Journal of human hypertension
卷号
25
期号
9
页码范围
532
出版商
Nature Publishing Group
简介
Resistant hypertension (RHTN) includes patients whose blood pressure (BP) is controlled with the use of four or more antihypertensive medications, and is referred to as ‘controlled resistant hypertension’(CRH). While specifically comparing patients with CRH and uncontrolled resistant hypertension (UCRH), we hoped to identify distinguishing characteristics that would provide insight into factors contributing to resistance to antihypertensive therapies. RHTN patients were identified as controlled (CRH, n= 43) or uncontrolled (UCRH, n= 47). No statistical differences were observed between the CRH and UCRH subgroups with respect to age and gender. The body mass index, aldosterone–renin ratio and pulse wave velocity (PWV) were significantly higher in UCRH patients. Although both subgroups showed increased cardiac mass, left ventricular mass index was significantly higher in UCRH compared with CRH …
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