作者
Yu‐Yan Pang, Jian‐Di Li, Li Gao, Xia Yang, Yi‐Wu Dang, Ze‐Feng Lai, Li‐Min Liu, Jie Yang, Hua‐Yu Wu, Rong‐Quan He, Zhi‐Guang Huang, Dan‐Dan Xiong, Li‐Hua Yang, Lin Shi, Wei‐Jia Mo, Deng Tang, Hui‐Ping Lu, Gang Chen
发表日期
2020/11
期刊
Cancer medicine
卷号
9
期号
21
页码范围
8004-8019
简介
Background
Hepatocellular carcinoma (HCC) remains one of the most common cancers worldwide and tends to be detected at an advanced stage. More effective biomarkers for HCC screening and prognosis assessment are needed and the mechanisms of HCC require further exploration. The role of MAOA in HCC has not been intensively investigated.
Methods
In‐house tissue microarrays, genechips, and RNAsequencing datasets were integrated to explore the expression status and the clinical value of MAOA in HCC. Immunohistochemical staining was utilized to determine MAOA protein expression. Intersection genes of MAOA related co‐expressed genes and differentially expressed genes were obtained to perform functional enrichment analyses. In vivo experiment was conducted to study the impact of traditional Chinese medicine nitidine chloride (NC) on MAOA in HCC.
Results
MAOA was …
学术搜索中的文章
YY Pang, JD Li, L Gao, X Yang, YW Dang, ZF Lai… - Cancer medicine, 2020