作者
Krista L Lanctôt, Luis Agüera-Ortiz, Henry Brodaty, Paul T Francis, Yonas E Geda, Zahinoor Ismail, Gad A Marshall, Moyra E Mortby, Chiadi U Onyike, Prasad R Padala, Antonios M Politis, Paul B Rosenberg, Emma Siegel, David L Sultzer, Eleenor H Abraham
发表日期
2017/1/1
来源
Alzheimer's & Dementia
卷号
13
期号
1
页码范围
84-100
出版商
No longer published by Elsevier
简介
Introduction
Apathy is common in neurocognitive disorders (NCDs) such as Alzheimer's disease and mild cognitive impairment. Although the definition of apathy is inconsistent in the literature, apathy is primarily defined as a loss of motivation and decreased interest in daily activities.
Methods
The Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART) Neuropsychiatric Syndromes Professional Interest Area (NPS-PIA) Apathy workgroup reviewed the latest research regarding apathy in NCDs.
Results
Progress has recently been made in three areas relevant to apathy: (1) phenomenology, including the use of diagnostic criteria and novel instruments for measurement, (2) neurobiology, including neuroimaging, neuropathological and biomarker correlates, and (3) interventions, including pharmacologic, nonpharmacologic, and noninvasive neuromodulatory approaches …
学术搜索中的文章
KL Lanctôt, L Agüera-Ortiz, H Brodaty, PT Francis… - Alzheimer's & Dementia, 2017