作者
Juan Manuel Mejı́a-Aranguré, Arturo Fajardo-Gutiérrez, Norma Isabel Reyes-Ruı́z, Roberto Bernáldez-Rı́os, Ana Marı́a Mejı́a-Domı́nguez, Susana Navarrete-Navarro, Ma del Carmen Martı́nez-Garcı́a
发表日期
1999/4/30
期刊
Archives of medical research
卷号
30
期号
2
页码范围
150-153
出版商
Elsevier
简介
BACKGROUND
Previous reports have shown that undernourished children with acute lymphoblastic leukemia (ALL) have a poorer long-term survival as compared with children with normal nourishment status. It has been shown that both the relapse and mortality rates of undernourished children with ALL are higher during the continuation phase of the chemotherapy and are apparently related to a poor tolerance of ablative chemotherapy. No previous articles have analyzed the early mortality rate of these patients.
METHODS
We carried out a case-control study, and have studied the effect of severe malnutrition on the mortality of 17 children with ALL during the initial induction-to-remission phase of the treatment. These 17 cases were compared with 76 controls who had survived at least the phases of induction and consolidation.
RESULTS
It was found that the chance of dying during the initial phase of the …
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