作者
Gabriel Ramalho-Ferreira, Leonardo Perez Faverani, Gustavo Antonio Correa Momesso, Eloá Rodrigues Luvizuto, Igor de Oliveira Puttini, Roberta Okamoto
发表日期
2017/6
期刊
Clinical oral investigations
卷号
21
页码范围
1485-1494
出版商
Springer Berlin Heidelberg
简介
Objectives
The aim of this study is to evaluate the alendronate and raloxifene influence in the alveolar healing process of osteoporotic rats.
Materials and methods
Sixty-four female rats were divided in four groups: sham rats (SHAM), ovariectomized rats and no medical treatment (OVX NT), ovariectomized rats and submitted to alendronate treatment (OVX ALE), and ovariectomized and submitted to raloxifene treatment (OVX RAL). The histomorphometrical and immunohistochemical analysis was performed. The quantitative data were analyzed through Kruskal-Wallis and Dunn tests (α = 0.05).
Results
In the longest period, SHAM and OVX RAL groups showed the better bone formation responses (P < 0.05). The worst bone formation response was observed in the group OVX NT. OVX RAL group showed the better …
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G Ramalho-Ferreira, LP Faverani, GAC Momesso… - Clinical oral investigations, 2017