作者
Douglas J Robertson, David A Lieberman, Sidney J Winawer, Dennis J Ahnen, John A Baron, Arthur Schatzkin, Amanda J Cross, Ann G Zauber, Timothy R Church, Peter Lance, E Robert Greenberg, María Elena Martínez
发表日期
2014/6/1
期刊
Gut
卷号
63
期号
6
页码范围
949-956
出版商
BMJ Publishing Group
简介
Objective
Some individuals are diagnosed with colorectal cancer (CRC) despite recent colonoscopy. We examined individuals under colonoscopic surveillance for colonic adenomas to assess possible reasons for diagnosing cancer after a recent colonoscopy with complete removal of any identified polyps.
Design
Primary data were pooled from eight large (>800 patients) North American studies in which participants with adenoma(s) had a baseline colonoscopy (with intent to remove all visualised lesions) and were followed with subsequent colonoscopy. We used an algorithm based on the time from previous colonoscopy and the presence, size and histology of adenomas detected at prior exam to assign interval cancers as likely being new, missed, incompletely resected (while previously an adenoma) or due to failed biopsy detection.
Results
9167 participants (mean age 62) were included in the analyses, with …
学术搜索中的文章
DJ Robertson, DA Lieberman, SJ Winawer, DJ Ahnen… - Gut, 2014