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Honey has been broadly recognized as a source of nourishment and medication by both old and new generations. It has been utilized by people to treat numerous illnesses through topical application for at least 2700 years, but recent researches have revealed the antiseptic and antimicrobial activities of honey. It has been seen as a powerful agent that can be used in various human pathologies. Different clinical examinations have affirmed that the use of honey to cutaneous injuries which are severely infected removes contamination from the injury and enhances tissue healing. Honey has been perceived as a successful antioxidant and antimicrobial agent for centuries. Utilized mainly for treating burns and surface wounds, it has thus been developed into clinical medicine, as medical grade honey. In spite of this, the underlying interest in the utilization of honey for antimicrobial treatment was significantly …