作者
Pieter W Holm, Riemer HJA Slart, Clark J Zeebregts, Jan L Hillebrands, René A Tio
发表日期
2009/1/1
来源
Annals of medicine
卷号
41
期号
4
页码范围
257-264
出版商
Taylor & Francis
简介
Vascular endothelial growth factor (VEGF), a potent growth factor for endothelial cells and inducer of angiogenesis, is important for endothelial integrity and thus for vascular function. On the other hand, VEGF may enhance the pathophysiologic mechanism of plaque formation and plaque destabilization. In this review we discuss the data available so far for VEGF as angiogenic and/or inflammatory cytokine in the vulnerable atherosclerotic plaque.
学术搜索中的文章
PW Holm, RHJA Slart, CJ Zeebregts, JL Hillebrands… - Annals of medicine, 2009