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To investigate associations of life‐time hazardous and binge drinking with biomarkers of cardiometabolic health, liver function, cardiovascular disease (CVD) and mortality.

Prospective cohort study with median follow‐up time to CVD incidence of 4.5 years.

London, UK: civil servants within the Whitehall II Study.

A total of 4820 drinkers aged 59–83 years with biological measurements during the 2011–12 survey.

Hazardous drinking was defined as having an AUDIT‐C score ≥ 5 calculated at each decade of life, forming the following groups: never hazardous drinker, former early (stopping before age 50), former later (stopping after age 50), current hazardous drinker and consistent hazardous drinker (hazardous drinker at each decade of life).

More than half the sample had been hazardous drinkers at some point during their life‐time, comprising former …