作者
Alexandra A Sawyer, Norman K Pollock, Bernard Gutin, Neal L Weintraub, Brian K Stansfield
发表日期
2019/5/1
期刊
Early human development
卷号
132
页码范围
24-29
出版商
Elsevier
简介
Background
Perinatal growth has important implications for cardiac development. Low birth weight is associated with cardiovascular (CV) events and mortality, and animal studies have shown that fetal growth restriction is associated with cardiac remodeling in the perinatal period leading to a permanent loss of cardiomyocyte endowment and compensatory hypertrophy.
Aims
To determine associations of birthweight (BW) and multiple proportionality indexes (body mass index (BMI); weight/length2 and Ponderal index (PI); weight/length3) at birth on one hand, with left ventricular (LV) structure and function during adolescence.
Subjects
379 healthy adolescents aged 14–18 years in Augusta, Georgia.
Outcome measures
LV structure and function parameters, including intraventricular septal thickness in diastole (IVSd), LV internal dimension in diastole (LVIDd), LV internal diameter in systole (LVIDs), LV posterior wall …
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AA Sawyer, NK Pollock, B Gutin, NL Weintraub… - Early human development, 2019