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Epidemiological findings demonstrating an increased risk for individuals with social anxiety disorder (SAD) to develop depression have been challenged by discrepant findings from prospective longitudinal examinations in childhood and early adolescence.

To examine patterns of SAD incidence, the consistency of associations of SAD with subsequent depression, and distal and proximal predictors for subsequent depression.

Face-to-face, 10-year prospective longitudinal and family study of up to 4 waves. TheDSM-IVMunich–Composite International Diagnostic Interview was administered by clinically trained interviewers.

Community sample in Munich.

Three thousand twenty-one individuals aged 14 to 24 years at baseline and 21 to 34 years at follow-up.

Cumulative incidence of SAD and depression (major depressive episode or dysthymia).