作者
Marina Salviato Balbão, Jaime Eduardo Cecílio Hallak, Emerson Arcoverde Nunes, Mauricio Homem de Mello, Andresa de Toledo Triffoni-Melo, Flavia Isaura de Santi Ferreira, Cristiano Chaves, Ana Maria Sertori Durão, Adriana Pelegrino Pinho Ramos, José Alexandre de Souza Crippa, Regina Helena Costa Queiroz
发表日期
2014/2
期刊
Therapeutic Advances in Psychopharmacology
卷号
4
期号
1
页码范围
30-36
出版商
SAGE Publications
简介
Objective
Olanzapine is an atypical antipsychotic drug used to treat schizophrenia. Some of the adverse effects related to its use are obesity, hyperlipidemia, type 2 diabetes and hypertension, which may result in development of metabolic syndrome. This study aimed to investigate a possible increase in some anthropometric and biochemical parameters, and the existence of any correlation between them in Brazilian patients with schizophrenia treated with olanzapine in the mid term.
Methods
Thirty subjects with schizophrenia were evaluated, 16 women and 14 men, aged between 18 and 47 years. All patients underwent blood collection and anthropometric measurements at four different times during 12 months of follow up; thus each patient was his or her own control.
Results
Evaluation of some anthropometric measurements showed significant differences when comparing the mean values obtained in each of the …
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M Salviato Balbão, JE Cecílio Hallak… - Therapeutic Advances in Psychopharmacology, 2014