作者
John H Gilmore, Feng Shi, Sandra L Woolson, Rebecca C Knickmeyer, Sarah J Short, Weili Lin, Hongtu Zhu, Robert M Hamer, Martin Styner, Dinggang Shen
发表日期
2012/11/1
期刊
Cerebral cortex
卷号
22
期号
11
页码范围
2478-2485
出版商
Oxford University Press
简介
Very little is known about cortical development in the first years of life, a time of rapid cognitive development and risk for neurodevelopmental disorders. We studied regional cortical and subcortical gray matter volume growth in a group of 72 children who underwent magnetic resonance scanning after birth and at ages 1 and 2 years using a novel longitudinal registration/parcellation approach. Overall, cortical gray matter volumes increased substantially (106%) in the first year of life and less so in the second year (18%). We found marked regional differences in developmental rates, with primary motor and sensory cortices growing slower in the first year of life with association cortices growing more rapidly. In the second year of life, primary sensory regions continued to grow more slowly, while frontal and parietal regions developed relatively more quickly. The hippocampus grew less than other subcortical …
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JH Gilmore, F Shi, SL Woolson, RC Knickmeyer… - Cerebral cortex, 2012