作者
Tábata de Paula Facioli, Stella V Philbois, Jens Tank, Ada Clarice Gastaldi, Bruno Augusto Aguilar, Ana Catarine da Veiga Oliveira, Lucas Dalvit Ferreira, Hugo Celso Dutra de Souza
发表日期
2023/7/1
期刊
Current Vascular Pharmacology
卷号
21
期号
4
页码范围
274-284
出版商
Bentham Science Publishers
简介
Background
Hypertension treatment with renin-angiotensin system inhibitors (RASi) presents contradictions about the recovery of damage in cardiovascular autonomic modulation characterized by reduced heart rate variability (HRV) and increased blood pressure variability (BPV). Conversely, the association of RASi with physical training can influence achievements in cardiovascular autonomic modulation.
Objective
To investigate the effects of aerobic physical training on hemodynamics and cardiovascular autonomic modulation in hypertensive volunteers untreated and treated with RASi.
Methods
A non-randomized controlled trial in which 54 men (≅ 40-60 years old) with a history of hypertension for >2 years were allocated in accordance with their characteristics into three groups: untreated (Control; n=16), treated with type 1 angiotensin II (AT1) receptor blocker (losartan; n=21), and treated with angiotensin …
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T de Paula Facioli, SV Philbois, J Tank, AC Gastaldi… - Current Vascular Pharmacology, 2023