作者
Hyun Woo Lee, Hyo-Jin Lee, Jung-Kyu Lee, Tae Yeon Park, Eun Young Heo, Deog Kyeom Kim
发表日期
2022/8/1
期刊
Chest
卷号
162
期号
2
页码范围
466-474
出版商
Elsevier
简介
Background
Impaired lung function is associated with a higher risk of developing lung cancer. However, lung function is a dynamic variable and must be evaluated longitudinally. This study reports on the relationship between accelerated lung function decline and development of lung cancer.
Research Question
Is accelerated lung function decline associated with the development of lung cancer?
Study Design and Methods
A longitudinal, observational study was performed by using epidemiologic data from two population-based studies comprising subjects assessed biannually from 2001 to 2019 in South Korea. Eligible subjects were between 40 and 69 years of age and were followed up by using spirometry. Spirometry measurements were made at each follow-up. Patients with a decline in FEV1 > 60 mL per year were defined as rapid FEV1 decliners. The relationship between lung cancer and rapid FEV1 decline …
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