作者
Gökhan Alpaslan, Cansu Alpaslan, Hakan Gögen, O Aynur, Sedat Çetiner, Ceyda Karadeniz
发表日期
1999/3/1
期刊
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
卷号
87
期号
3
页码范围
317-321
出版商
Mosby
简介
Objective
The purpose of this study was to evaluate the effects of chemotherapy on oral and dental structures and craniofacial growth in 30 survivors of childhood lymphoma.
Study Design
Eruption status, root malformations, premature apexification, agenesis, crown anomalies, soft tissue abnormalities, gingival and periodontal status, enamel defects and discolorations, and craniofacial growth status of the subjects were documented and compared with findings in 20 healthy children who served as controls.
Results
Statistically significant (P < .05) differences between the study and control groups were found for plaque index, enamel hypoplasias, discolorations, and agenesis.
Conclusions
The results of the study suggest that antineoplastic therapy and/or childhood cancer can result in a higher prevalence of various malformations in teeth. Children treated in the early years of their lives displayed the most severe …
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G Alpaslan, C Alpaslan, H Gögen, O Aynur, S Çetiner… - Oral Surgery, Oral Medicine, Oral Pathology, Oral …, 1999