作者
Tomas Vita, Christoph Gräni, Siddique A Abbasi, Tomas G Neilan, Ethan Rowin, Kyoichi Kaneko, Otavio Coelho-Filho, Eri Watanabe, Francois-Pierre Mongeon, Hoshang Farhad, Carlos Henrique Rassi, Yuna L Choi, Kathleen Cheng, Michael M Givertz, Ron Blankstein, Michael Steigner, Ayaz Aghayev, Michael Jerosch-Herold, Raymond Y Kwong
发表日期
2019/8
期刊
JACC: Cardiovascular Imaging
卷号
12
期号
8 Part 2
页码范围
1659-1669
出版商
American College of Cardiology Foundation
简介
Objectives
In patients with nonischemic dilated cardiomyopathy (NIDCM), native T1, partition coefficient (λGd), and extracellular volume fraction (ECV) mapping may offer prognostic values beyond late gadolinium enhancement (LGE), by scaling the range of myocardial changes.
Background
In patients with NIDCM, LGE is seen in 30% of patients and it indicates adverse prognosis.
Methods
The study mapped 6 anatomical locations using all 4 cardiac magnetic resonance (CMR) tissue-characterizing methods and associated with outcome. The authors performed T1 mapping of the myocardium and the blood pool, before and serially after contrast injection, using a Look-Locker cine gradient-echo technique to obtain T1 and the corresponding reciprocal R1 values. λGd values were derived from the slopes of the least-squares regression lines for myocardial versus blood R1, then adjusted to serum hematocrit to yield …
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T Vita, C Gräni, SA Abbasi, TG Neilan, E Rowin… - JACC: Cardiovascular Imaging, 2019