作者
Wojciech Cytawa, Anna Katharina Seitz, Stefan Kircher, Kazuhito Fukushima, Johannes Tran-Gia, Andreas Schirbel, Tomasz Bandurski, Piotr Lass, Markus Krebs, Wojciech Połom, Marcin Matuszewski, Hans-Jürgen Wester, Andreas K Buck, Hubert Kübler, Constantin Lapa
发表日期
2020/1
期刊
European journal of nuclear medicine and molecular imaging
卷号
47
页码范围
168-177
出版商
Springer Berlin Heidelberg
简介
Purpose
The present study is based on a retrospective analysis of Gallium-68 (68Ga)-labelled prostate-specific membrane antigen (68Ga-PSMA I&T) PET/CT performed in newly diagnosed, treatment-naïve prostate cancer (PCa) patients prior to definitive treatment.
Methods
A total of 82 men were included in the study and were imaged with 68Ga-PSMA I&T PET/CT to assess the distribution of PSMA-avid disease for staging purposes (11 with low-risk, 32 with intermediate-risk, and 39 with high-risk PCa). Forty patients (20 with intermediate- and 20 with high-risk disease) underwent subsequent radical prostatectomy with extended pelvic lymph node dissection which allowed for correlation of imaging findings with histopathologic data.
Results
PSMA-positive disease was detected in 83% of patients with 66/82 (80.5 …
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W Cytawa, AK Seitz, S Kircher, K Fukushima… - European journal of nuclear medicine and molecular …, 2020