作者
M Chakhtoura, EA Akl, S El Ghandour, K Shawwa, A Arabi, Z Mahfoud, RH Habib, H Hoballah, G El Hajj Fuleihan
发表日期
2017/1
来源
Osteoporosis International
卷号
28
页码范围
35-46
出版商
Springer London
简介
Summary
In the Middle East and North Africa (MENA), a vitamin D dose ≥2000 IU/day may be needed to allow to the majority of the population to reach the target 25-hydroxyvitamin D (25(OH)D) level ≥20 ng/ml. Data in the region on the effect of vitamin D supplementation on various skeletal and extra-skeletal effects are scarce.
Introduction
Hypovitaminosis D is prevalent worldwide, more so in the Middle East and North Africa (MENA). This study aims to determine the effects of vitamin D replacement on the mean difference in 25-hydroxyvitamin D [25(OH)D] level reached and other outcomes, in the MENA.
Methods
This is a meta-analysis of randomized trials from the MENA, administering vitamin D supplementation for at least 3 months, without language or time restriction. We conducted a comprehensive search in …
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