查看文章

Background:

Subclinical cardiovascular disease is inherent in complications of diabetes mellitus. It occurs before the obvert manifestation of cardiovascular disease complication in diabetes, and involves vasculopathy triad or three major vascular events comprising stasis, endothelial dysfunction, and atherothrombosis.

Aim:

This study was to examine evidence of vasculopathy triad in prediabetes, biomarkers of stasis, endothelial dysfunction, and atherothrombosis in prediabetes were compared with apparently healthy group.

Materials and Methods:

Eighty-one participants with results for plasma D-dimer, homocysteine, and whole blood viscosity were selected from a research database. The participants consisted of control (n= 44) and prediabetes (n= 37) based on clinical history and laboratory results.

Results:

Multivariate analysis shows a significantly higher level of vasculopathy in prediabetes than in the control …